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On the contrary, cells treated with BSO maintained their nuclear glutathione level as well as the high expression of Id2 and normal cell growth

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This affects the upstream metabolites in the methionine and transsulfuration pathways because GSSG inhibits the enzymes MAT-I and MAT-III [57, 58]

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Laboratory investigations indicate that glutathione administration could influence markers of oxidative stress and immune responses, highlighting interesting research possibilities for overall physiological function

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